top of page

Lissencephaly

Etymology:

Definition:

Gr. lissós: “smooth” +‎ Gr. encephal: “brain” +‎  Gr. en, “in” +‎ Gr. kephalḗ: "head”

A rare brain disorder whereby the whole or parts of the surface of the brain appear smooth. It is caused by defective neuronal migration during the 12th to 24th weeks of gestation resulting in a lack of development of brain folds (gyri) and grooves (sulci).

bottom of page